Rejuran: What Is It and How Does It Work?
- Alice
- May 24
- 2 min read

A Gentle Introduction to Polynucleotide-Based Skin Rejuvenation
At Through the Looking Glass Clinic, we’re all about skin confidence—inside and out. If you’ve been hearing the word “Rejuran” pop up in skin circles lately, you’re not alone. Known for its unique approach to supporting skin quality and integrity, Rejuran is gaining interest among clients looking for treatments beyond traditional injectables.
But what exactly is it—and how does it work? Let’s break it down.
What Is Rejuran?
Rejuran is a skin injectable that contains polynucleotides (PN), which are fragments of DNA derived from salmon. These molecules are highly purified and biocompatible with human skin. Polynucleotides are believed to support the skin’s own regenerative processes and contribute to overall skin health.
It is not a filler and not a muscle relaxant—it falls into a category of treatments known as skin boosters or biostimulators, which work on the skin itself rather than changing structure or expression.
What Does Rejuran Aim to Do?
Because of TGA guidelines, we can’t list specific outcomes. However, Rejuran is often considered during consultations for clients who are:
Concerned with dull, uneven, or tired-looking skin
Exploring options for texture refinement
Interested in a more hydrated, radiant-looking complexion
Seeking a gentle treatment that supports skin integrity over time
Our approach is always personalised, and Rejuran may be recommended as part of an overall skin health plan.
How Does It Work?
Polynucleotides are believed to support cell turnover, improve hydration, and assist the skin’s natural repair processes. Rejuran is typically injected into the superficial layer of the skin using a fine needle or microinjection technique.
This process may help the skin function at a more optimal level and encourages a smoother, more balanced appearance over time. Your results will depend on a range of factors, including your skin condition, age, lifestyle, and how consistently treatments are performed.
What Is the Process Like?
At Through the Looking Glass Clinic, your Rejuran journey begins with a full consultation. If suitable, the treatment is performed in-clinic and typically takes around 30–45 minutes. A topical numbing cream may be used to enhance comfort.
Mild redness or swelling can occur and usually settles within 24–48 hours. Aftercare instructions will be provided to support your skin’s recovery.
How Many Treatments Will I Need?
A series of sessions may be recommended for best results, with ongoing maintenance depending on your goals. Every skin journey is unique, and we’ll work with you to create a plan that suits your lifestyle and skin priorities.
Who Is Rejuran Suitable For?
Rejuran may be suitable for a wide range of skin types and ages. It’s often selected by clients looking for treatments that support skin wellness and radiance without altering facial features.
Your practitioner will determine whether it’s appropriate for you during your consultation, considering your medical history and aesthetic goals.
Let’s Talk About It
If you're ready to explore advanced skin treatments and want advice that’s honest, personalised, and pressure-free—we’re here to guide you.
✨ Book your consultation at www.ttlgc.com.au📲 Follow along @aesthetics_with_alice for education and real client journeys
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